In 1909, the biologist Wilhelm Johannsen wrote "It appears as most simple to use the last syllable 'gen' taken from Darwin's well-known word "pangene"... Thus we will say for... pangene simply...Gene. "
1. Why am I unique?
1.1 Distinguish between inherited (genetic) and acquired (environmental) characteristics.
1.2 Investigate the structure of DNA.
1.3 Relate DNA base sequences to the production of particular proteins, resulting in an organism’s traits.
1.4 Draw and interpret a flowchart describing the relationship between DNA, genes and chromosomes.
1.5 Model the steps to identify the role of meiosis (cell division) in halving the number of chromosomes as gametes (male and female sex cells) are formed.
1.6 Describe how fertilisation combines the chromosomes in the male and female sex cells to form new combinations of genes in the zygote.
1.7 Define mutation and identify causes, including through DNA replication.
1.8 Give examples and explain how mutations can give advantages or disadvantages to an organism.
2. How can brown-eyed parents have a blue-eyed child?
2.1 Use the terms genotype, phenotype, allele, dominant, recessive to explain the process of dominant/recessive inheritance.
2.1B *Enrichment: Outline Mendel’s monohybrid experiments and the discovery of dominant/recessive traits.
2.2 Construct Punnett squares to identify probable offspring from dominant /recessive inheritance crosses.
2.2B *Extension: Construct Punnett squares to identify probable offspring from co-dominance and incomplete dominance crosses.
2.3 Interpret Pedigree charts of dominant/recessive inheritance
2.3B Interpret Pedigree charts of co-dominance and/or construct Pedigree charts
2.4 Identify the role of X and Y chromosomes in determining gender.
3. Science future or Science fact?
3.1 Outline a range of biotechnology techniques.
3.2 Identify social and ethical issues associated with the use of biotechnology.
3.3 Develop skills to analyse the validity of secondary sources.
3.4 Use the ABCDE Scaffold to assess secondary sources.
3.5 Identify the role of scientists in the research and development of our understanding of genetic diseases and applying biotechnology.