DL Week 1

Monday Week 1 P5 L4

PL Day

Wednesday Week 1 P3 L3

IQ1 Why am I unique?

1. Why am I unique?

1.1 Distinguish between inherited (genetic) and acquired (environmental) characteristics.

1.2 Investigate the structure of DNA.

1.3 Relate DNA base sequences to the production of particular proteins, resulting in an organism’s traits.

1.4 Draw and interpret a flowchart describing the relationship between DNA, genes and chromosomes.

1.5 Model the steps to identify the role of meiosis (cell division) in halving the number of chromosomes as gametes (male and female sex cells) are formed.

1.6 Describe how fertilisation combines the chromosomes in the male and female sex cells to form new combinations of genes in the zygote.

1.7 Define mutation and identify causes, including through DNA replication.

1.8 Give examples and explain how mutations can give advantages or disadvantages to an organism.

Task 1.0A Pre-test:

Join class https://quizizz.com/join?class=C462753

PreTest 1 code 4487 8194

PreTest 2 code 4422 2834

INTRODUCTION

View videos:

Gattaca trailer https://www.youtube.com/watch?v=BpzVFdDeWyo [2.26 mins]

This film was released in 1997. At that time, a significant part of it was science fiction. Today, much of it is science possible , even science fact.

In this topic we will explore th "brave new world" of genetics and biotechnology.

View videos:

Animal Pharm Part 1 [https://www.youtube.com/watch?v=tYeu2fG87T4 [10 mins]

Animal Pharm Part 2 https://www.youtube.com/watch?v=7QQ7SiCgORQ [10 mins]

ONGOING TASK

Glossary of terms:

As we move through this topic, there are some terms you may come across that you will need to understand, and some others that may be helpful. Start a glossary of terms.

Essential:

alleles, anaphase, asexual reproduction, binary fission, bioethics, biotechnology, chromosome, cloning, cytokinesis, daughter cell, DNA, diploid, dominant, embryo, ethical, gamete, gene, genotype, gonad, haploid, heredity, heterozygous, homozygous, hybrid, inheritance, interphase, in-vitro, meiosis, metaphase, mitosis, mutation, offspring, phenotype, probability, prophase, Punnett square, purebred, recessive, replication, sex determination, sexual reproduction, stem-cell research, telophase, traits, zygote

Extension terms:

independent assortment, co-dominance, incomplete dominance, sex-linked inheritance
Reference Text pages 46,47.

1.1 Distinguish between inherited (genetic) and acquired (environmental) characteristics.

ACTIVITY 1.1A Nature or nurture: inherited or developed?

1. List some characteristics you have that are like other members of your family, things you think you have inherited (eg colour of your eyes).

2. Complete the worksheet below by:

answering the questions for your natural state (not blue hair), then
ticking the answers you think are something you were born with (nature), not something you have developed in your life (nurture).

ology_naturenurturequiz.pdf

TASK 1.0B How am I unique?

1. Follow the instructions from the website: https://learn.genetics.utah.edu/content/basics/activities/pdfs/InventoryOfTraits.pdf to collect data from classmates and/orfriends.

2. Compile data into a table with three columns: name of trait, percentage with trait, percentage without trait.

3. Convert the data into a column graph.

4. In paragraphs, using sentences of up to 13 words, describe and explain any patterns or trends you might see in the data.

ACTIVITY 1.1B

Traits: One by one - stand, sit.

All stand. One student will call out their traits. Sit down if you do not share the trait.

How unique are you across 11 traits?

Complete survey on whiteboard.

ACTIVITY 1.1B What is my "genetic number"?

A "genetic number" is just a fun way of showing how unique we are across a small range of traits. Gattaca would use this for millions of traits.

Follow the instructions from the left box to find your genetic number. How many people in your wider family have a number the same as yours? Test them to see.

10 WDWCF 1.3e Find Genetic Number PPT.pptx

10 DL Find Genetic Number WS.docx

Biologist Teghan Lucas, from the University of Adelaide in Australia, and her team examined 4,000 different faces from the US Anthropometric Survey (ANSUR) database – a record of anthropometric data created by the US Army to keep track of the bodily measurements of soldiers. The team measured and compared them across eight distinct facial features - although they didn't disclose which features these were. The mthematical modelling concluded that the chance of someone looking exactly like someone else in the world for all eight features is about one in 1 trillion, or 0.0000000001%.

This was a sampling of only eight possible characteristics (traits), and we have so very many more than that! So imagine how much further you would move away from having someone just like you in the world.

In the following two activities, you can test some of this for yourself. Try to do 1.1.1 with people not related to you, and 1.1.2 with people from your wider family.

From https://www.sciencealert.com/here-s-the-chances-of-you-having-a-doppelgaenger

1.2 Investigate the structure of DNA.

view videos The DNA Song:

https://www.youtube.com/watch?v=_6ESQ2qILjA [2.46 mins]
https://www.youtube.com/watch?v=T5gEIViVAPw [1.56 mins]
https://www.youtube.com/watch?v=wdhL-T6tQco [4.32]

write anything you remember, anything you wonder

Task 1.2A

10 WDWCF 1.2b DNA PPT wb.pptx

10 WDWCF 1.2b DNA WS1 ppt.pdf

Rosalind Franklin, Chemist & Molecular Biologist

Photo: Donaldson Collection/Michael Ochs Archives/Getty Images

Born in 1920 in London, Rosalind Franklin was a chemist, X-ray crystallographer and leading molecular biologist who discovered the structure of DNA.

In 1951 Franklin became a research associate at King's College in London where she used X-ray crystallography techniques on DNA. A year later Franklin captured an image of the molecule's structure, identifying it as Photo 51.

While doing her research, however, her relationship with her colleague Maurice Wilkins became unpleasant, so she left King's College and continued her work at Birkbeck College.

Unknown to Franklin, Wilkins took Photo 51 and shared it with Francis Crick and James Watson, who used her research to publish their double-helix theory of DNA in 1953. Franklin published her own separate research on the same theory shortly thereafter. However, her manuscript was dismissed as merely confirming her male colleagues' discovery.

In 1958, aged 37, Franklin died from ovarian cancer, never knowing her research was stolen. Four years later, Wilkins, Crick and Watson would go on to receive the Nobel Peace Prize for their double-helix theory of DNA. Watson would later author the book, The Double Helix, in which he continued to credit himself and his male colleagues for their award-winning discovery and to describe Franklin as an antagonistic and overly-emotional woman.

Adapted from https://www.biography.com/news/alice-ball-female-scientists

Task 1.2B

Summarise notes from text pp2-6

Task 1.2C

STILE lessons

Decoding Life: DNA

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